Ketamine vanquishing depression?

Medexpress pushed this decade long quest into ketamine back at me a few days ago with “Scientists explain how ketamine vanquishes depression within hours“. It took my catching sight of the work, once again, emerging from Yale School Of Medicine, just as it did nearly a decade ago, to snag my attention.

With a couple of taps on my iPad I found myself over on the Yale website reading, their article which put this paragraph in front of me:

“In their research, Duman and others show that in a series of steps ketamine triggers release of neurotransmitter glutamate, which in turn stimulates growth of synapses.   Research at Yale has shown that damage of these synaptic connections caused by chronic stress is rapidly reversed by a single dose of ketamine.”

After shifting over to my lap top, I took another step and watched “New Mechanism Elicited with Ketamine in Treatment-resistant depression“. Fortunately, at no point did anyone push the idea of our finally being able to completely end depression. What has been suggested is that we may have found a completely new avenue down which to trod in trying to deal with an old and crotchety problem.

Keep an eye on this for yourself. Who knows, inside the next decade we may seen another potential means of quickly dealing with depression.


About the post

addiction, depression, General, medical, mental health

One Comment

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  1. I was excited when I found out about this new discovery too. A friend of mine recently went on an SSRI for extreme depression and during lunch one day he expressed his frustration. “So you mean I have to manage to not kill myself for the next three weeks before we find out if this MIGHT work…oh and by the way you’re going to feel worse while you’re waiting?!” Hope we continue with discoveries like this–

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